Antibody Production Services

At Bio X Cell, we know that growing hybridoma cells and purifying antibodies in large quantities with low endotoxin levels can be technically challenging and time-consuming.

Enlist our experienced team to do this for you! Bio X Cell’s optimized fermentation process produces more antibody in less time than traditional methods. A technical project manager will guide you through the process, providing recommendations and updates along the way.

Request Contract Production Quote

Our Services Include:

We know that research moves at a fast and precise pace, and we aim to partner with you to achieve your goals. Our platform is customizable, allowing you to collaborate with our team to select à la carte services that improve the rigor of your experimental design. If you do not see a service listed, contact us at contractservices@uat.bioxcell.com to provide more details about your project.

Request Contract Production Quote

Project Workflow

Phase
1. Pilot Instructions for preparing and shipping cells.
Assessment of cell line activity utilizing a small scale cell culture followed by either protein A or G affinity purification.
Mycoplasma testing service.
Antibody isotyping service.
2. Fermentation Cell culturing and monitoring 7 days/week.
Freezing of five vials of cells.
Storage of cells at Bio X Cell for rapid re-supply.
Expansion of cells using optimized fermentation process.
3. Purification Purification of supernatant on Protein A or G.
Buffer exchange to PBS that is preservative and stabilizer-free.
Sterile filtering of final product.
  • Testing to confirm <2EU/mg endotoxin.
  • <1EU/mg endotoxin level is available for an added charge.
4. Vialing and QC
  • Sterile vialing of finished product.
  • Custom aliquoting available.
Internal antibody quality assessment.
Certificate of Analysis.
Murine pathogen screening service.
5. Shipping Shipping on cold packs in environmentally friendly packaging.
Request Contract Production Quote
james@2x

"I am totally satisfied with the service Bio X Cell has given us. When anyone asks me for CTLA-4 antibodies, I always refer them to you. I look forward to another 20 years."

- James P. Allison

Co-Recipient of the 2018 Nobel Prize in Physiology or Medicine

Customer Testimonials

"Very reliable antibodies! Especially for functional experiments."

- Amit Singh

NIH

"I used lots of in vivo depletion antibodies from bioxcell. Their products and service are fantastic"

- Jintao Xu

University of Michgan

"Excellent, it works very well."

- Piu Saha

University of Toledo

"Good service"

- Smrithi S Menoon

The University of Toledo

"Our lab has been using Bio X Cell exclusively for the last few years and have a wonderful experience working with the company!"

- Ahmed Abokor

University of Toledo

"Very reliable antibodies! Especially for functional experiments."

- Amit Singh

NIH

"I used lots of in vivo depletion antibodies from bioxcell. Their products and service are fantastic"

- Jintao Xu

University of Michgan

"Excellent, it works very well."

- Piu Saha

University of Toledo

"Good service"

- Smrithi S Menoon

The University of Toledo

"Our lab has been using Bio X Cell exclusively for the last few years and have a wonderful experience working with the company!"

- Ahmed Abokor

University of Toledo