InVivoMAb anti-mouse TCRβ
Product Details
The H57-597 monoclonal antibody reacts with the beta chain of the mouse T cell receptor (TCR). TCRβ belongs to the immunoglobulin superfamily and is expressed by thymocytes and T lymphocytes. TCRβ combines with TCRα to form TCR α/β. TCR α/β plays a central role in antigen recognition, signal transduction, and T cell activation. The H57-597 antibody has been shown to deplete TCR α/β bearing T cells following in vivo administration.Specifications
Isotype | Armenian hamster IgG |
---|---|
Recommended Isotype Control(s) | InVivoMAb polyclonal Armenian hamster IgG |
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Immunogen | Affinity purified TCR from mouse DO-11.10 cells |
Reported Applications | in vivo T cell depletion |
Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin |
<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Sterility | 0.2 μM filtered |
Production | Purified from tissue culture supernatant in an animal free facility |
Purification | Protein G |
RRID | AB_10950158 |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
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