RecombiMAb human IgG4 S228P L235E P329G (SPLEPG) isotype control, anti-hen egg lysozyme
Catalog #CP148
Product Details
This human IgG4 isotype control antibody reacts with hen egg lysozyme and has low or no specific binding to any human sample. The S228P substitution is included to prevent Fab-arm exchange. The P329G substitution combined with S228P and L235E substitutions has been shown to decrease effector functions by disrupting the Fc/FcĪ³ receptor interface.Specifications
| Isotype | Human IgG4 |
|---|---|
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Mutations | S228P, L235E, P329G (SPLEPG) |
| Immunogen | Hen egg lysozyme (HEL) |
| Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin |
<1EU/mg (<0.001EU/Ī¼g) Determined by LAL gel clotting assay |
| Sterility | 0.2 Āµm filtration |
| Production | Purified from CHO cell supernatant in an animal free facility |
| Purification | Protein A |
| RRID | AB_2927522 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4Ā°C. Do not freeze. |
Additional Formats
Recommended Products
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Recommended Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer
