Accelerating breakthroughs with expert conjugation
Bio X Cell’s experts can help you tackle the complexities and time-consuming nature of conjugation chemistry and the purification of conjugated antibodies. We’ve coupled our industry-leading antibodies and optimized antibody production services with expert conjugation capabilities to support your breakthrough discoveries.
| Phase | Description | Included | Optional Add-Ons |
|---|---|---|---|
| Antibody Engineering & Design | Bio X Cell’s in-house experts design the antibody to your desired specs | ![]() | |
| DNA synthesis to support transfection volumes of 1L or less | ![]() | ||
| Maxi, mega, and gigaprep options to produce DNA to support large-scale expression | ![]() | ||
| Pilot | Assessment of antibody expression levels to determine scale-up volume | ![]() | |
| Purify small amount of antibody to ship for testing | ![]() | ||
| Transfection | Transfection of one or more plasmids into HEK293 or CHO cells in volumes from 100ml to 20L | ![]() |
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| Addition of enhancers to increase yield | ![]() |
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| Concentration of cell supernatant | ![]() |
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| Purification | Purification of supernatant over Protein A or G | ![]() |
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| Buffer exchange to PBS (preservative & stabilizer free) | ![]() |
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| Sterile filtering | ![]() |
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| Testing to confirm ≤1 EU/mg endotoxin levels; additional testing and antibody purification services available | ![]() |
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| Vialing & QC | Sterile vialing of finished product | ![]() |
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| Internal quality assessment | ![]() |
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| Certificate of Analysis (CoA) | ![]() |
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| Analytical Size Exclusion Chromatography | ![]() | ||
| Murine pathogen screening service | ![]() | ||
| Shipping on cold packs in environmentally friendly packaging | ![]() |
| Phase | Description | Included | Optional Add-Ons |
|---|---|---|---|
| Project Initiation | Consult our technical team to choose the best dye and conjugation chemistry for your end-use assay | ![]() |
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| Provide your project-specific details and choose from our wide selection of labels | ![]() |
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| Acquire the Antibody of Interest | Purchase a Bio X Cell catalog antibody | ![]() | |
| Enlist Bio X Cell to custom-produce an antibody from your IP | ![]() | ||
| Contact our team at contractservices@bioxcell.com for help sourcing the antibody | ![]() |
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| Conjugation & Purification | Conjugation reaction, incorporating ASO, fluorochrome, biotins or synthetic dyes | ![]() |
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| Removal of unconjugated ASO, fluorochrome, dye, or biotin | ![]() |
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| Sterile filtering of the final product | ![]() |
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| Vialing & QC | If appropriate, measurement of antibody concentration and fluorescence to protein (F/P) ratio | ![]() |
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| Additional QC: HPLC or Mass spec | ![]() | ||
| Sterile vialing of finished product | ![]() |
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| Custom aliquoting available | ![]() | ||
| Certificate of Analysis (CoA) | ![]() |
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| Shipping | Shipping on cold packs | ![]() |
Our antibody conjugation capabilities allow us to meet the evolving needs of biotherapeutics researchers.
Wide selection of catalog antibodies
Diverse conjugation options
Conjugated isotype control antibodies
Ready for in vivo use
Large volume capacity
Rapid turnaround
Select from Diverse Antibody Conjugation Options
Bio X Cell provides antibodies of exceptional quality and the conjugation capabilities and expertise needed to support your research.
Choose from our catalog or design a custom antibody by leveraging our contract antibody production services.
Select chemistry to avoid using reagents that could compromise downstream applications and experiments.
While our team's conjugation expertise is extensive, some of the most common conjugates include:
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Antisense Oligonucleotides (ASO) for Delivery
ASOs can directly target specific cells or tissues, enhancing therapeutic efficacy. -
In Vivo Imaging Dyes
We can label your antibody with imaging dyes to facilitate non-invasive, real-time tracking of biological processes, aiding in diagnostics and treatment monitoring. -
Biotin
Biotin conjugation to facilitate the simultaneous detection of multiple targets, enhancing assay throughput and flexibility. -
Fluorochromes
Fluorochrome and custom labeling options for applications like flow cytometry, immunofluorescence microscopy, and other fluorescence-based assays.
InVivoMAb™ products are subjected to rigorous quality control (QC) assessments for purity, pathogen testing, and functionality. Additionally, optional services, such as murine pathogen screening, are available for projects requiring higher QC standards.
Visualize Clearly with Custom Fluorochrome-Labeled Antibodies
Our top-tier antibodies are perfect for your fluorescence-based assay. We can make conjugates for flow cytometry, microscopy, ELISA, IHC, TR-FRET, and more.
Spectra for Flow Cytometry
Emission Curves
See all InVivoPlus™ AntibodiesBrowse Our Antibody Labels
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Antibody Conjugation Production Project Workflow
Explore Our Comprehensive Custom Antibody Solutions
Hybridoma & Stable Cell Line Production Services
Antibody Engineering & Recombinant Production Services
QC, Purification & Precision Services
Consult With Bio X Cell to Enable Your Next Breakthrough Discovery
Whether you need antibody customization or high-volume production, Bio X Cell is committed to advancing your therapeutic innovations.
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Antibody
Conjugation Chemistry
Conjugate Selection
Screening and Analysis