In Vitro Neutralization & Blocking

Bio X Cell provides functionally validated antibodies that neutralize or block specific proteins and pathways in vitro. These reagents are widely used in animal models to dissect signaling mechanisms, validate functional outcomes, and evaluate therapeutic strategies.

Bio X Cell offers antibodies against key cytokines, receptors, and checkpoint proteins, including:

• Cytokines: TNF-α, IL-1β, IL-6, IL-10, IL-12p40, IFN-γ, TGF-β
• Receptors: IL-6R, IL-10R, IFNAR1, CD40L, CD28
• Immune Checkpoints: PD-1, PD-L1, CTLA-4, LAG-3, TIGIT

All antibodies for in vitro assays from Bio X Cell are formulated to meet the same standards as those developed for in vivo research. All antibodies are ultrapure (≥95% purity), demonstrate low endotoxin levels (as low as ≤0.5 EU/mg), and contain no preservatives, stabilizers, or carrier proteins. Each lot is provided with a Certificate of Analysis (CoA) to ensure reproducibility quality assurance for every experiment.