InVivoMAb anti-human TROP-2
Catalog #BE0408
Clone:
Pr1E11
Reactivities:
Human
Product Details
The Pr1E11 monoclonal antibody reacts with human TROP-2, also known as TACSTD2, EGP-1, and GA733-1. TROP-2 is a type I transmembrane glycoprotein with high homology to TROP-1/EpCAM. TROP-2 spans the epithelial membrane surface and plays a role in embryonic development, cell self-renewal, proliferation, and transformation. TROP-2 is found on the surface of multiple normal epithelial tissues, including skin and oral mucosa. TROP-2 can promote tumor growth and its overexpression is common in many types of malignant epithelial tumors. A variety of human epithelial cancer cells are characterized by TROP-2 overexpression, including breast, lung, urothelial, gastric, colorectal, pancreatic, prostatic, cervical, head and neck, and ovarian carcinomas.Specifications
| Isotype | Mouse IgG1, Īŗ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb mouse IgG1 isotype control, unknown specificity |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Immunogen | Primary human prostate cancer cells |
| Reported Applications |
Western blot Immunohistochemistry (frozen) Flow cytometry |
| Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin |
<2EU/mg (<0.002EU/Ī¼g) Determined by LAL gel clotting assay |
| Sterility | 0.2 Āµm filtration |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4Ā°C. Do not freeze. |
Recommended Products
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Recommended Isotype Control(s)
InVivoMAb mouse IgG1 isotype control, unknown specificity
-
Recommended Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer
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