InVivoMAb anti-mouse VEGF-A
Catalog #BE0399
Clone:
2G11-2A05
Reactivities:
Mouse
Product Details
The 2G11-2A05 monoclonal antibody reacts with mouse VEGF-A (vascular endothelial growth factor A). VEGF-A is a 45 kDa homodimeric, disulfide-linked glycoprotein that plays key roles in angiogenesis, vasculogenesis, and endothelial cell growth. It promotes mitogenesis, chemotaxis, and vascular permeability. Most tumors have a requirement for angiogenesis, and inhibition of VEGF binding to VEGF receptors has been the focus of several tumor therapeutic strategies. The 2G11-2A05 antibody neutralizes the biological activity of VEGF-A.Specifications
| Isotype | Rat IgG2a, Īŗ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb rat IgG2a isotype control, anti-trinitrophenol |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Immunogen | N-terminal 24 AA sequence of murine VEGF |
| Reported Applications |
in vivo VEGF-A neutralization Western blot |
| Formulation |
PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin |
<2EU/mg (<0.002EU/Ī¼g) Determined by LAL gel clotting assay |
| Sterility | 0.2 Āµm filtration |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4Ā°C. Do not freeze. |
Recommended Products
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Recommended Isotype Control(s)
InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
-
Recommended Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer
