InVivoSIM anti-human IgE (Omalizumab Biosimilar)

Catalog #SIM0016
Clone:
Omalizumab
Reactivities:
Human

$217.00 - $7,526.00

$217.00 - $7,526.00

Choose an Option...
  • 100 mg - $7,526.00
  • 50 mg - $4,229.00
  • 25 mg - $2,942.00
  • 5 mg - $843.00
  • 1 mg - $217.00
  • Custom Amount (Quotes Only)
In stock
Only %1 left

Product Details

This non-therapeutic biosimilar antibody uses the same variable regions from the therapeutic antibody Omalizumab making it ideal for research use. This Omalizumab biosimilar reacts with free human IgE in blood and interstitial fluid and to membrane-bound IgE on the surface of IgE-expressing B cells. It does not bind to IgE that is already bound by the high affinity IgE receptor (FcĪµRI) on the surface of mast cells, basophils, and antigen-presenting dendritic cells. It does not provoke histamine release from mast-cells sensitised by IgE. Omalizumab binds an epitope in proximity to the binding site of the FcĪµRI.

Specifications

Isotype Human IgG1, Īŗ
Recommended Isotype Control(s) RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme
Recommended Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Immunogen Human IgE
Reported Applications IgE neutralization
Flow cytometry
ELISA
Formulation PBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin <1EU/mg (<0.001EU/Ī¼g)
Determined by LAL gel clotting assay
Sterility 0.2 Āµm filtration
Purification Protein A
RRID AB_2927532
Molecular Weight 150 kDa
Storage The antibody solution should be stored at the stock concentration at 4Ā°C. Do not freeze.